Trans-synaptic degeneration of the optic radiation from optic nerve atrophy
نویسندگان
چکیده
منابع مشابه
Longitudinal evidence for anterograde trans-synaptic degeneration after optic neuritis.
In multiple sclerosis, microstructural damage of normal-appearing brain tissue is an important feature of its pathology. Understanding these mechanisms is vital to help develop neuroprotective strategies. The visual pathway is a key model to study mechanisms of damage and recovery in demyelination. Anterograde trans-synaptic degeneration across the lateral geniculate nuclei has been suggested a...
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1 Istituto Scientifico San Raffaele, Milano, Italy 2 Studio Oculistico d’Azeglio, Bologna, Italy 3 IRCCS, Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy 4 Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy 5 IRCCS Fondazione Bietti, Roma, Italy 6 Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine at the Un...
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Corticosteroids shorten the period of functional impairment following relapses in optic neuritis and multiple sclerosis (MS); however they have not, thus far, been shown to affect the final level of function compared with placebo. There has been recent interest in the use of corticosteroids as neuroprotective agents by their effect of decreasing nitric oxide (NO) production by mononuclear cells...
متن کاملThe optic syrinx: cavernous degeneration of the optic nerve demonstrated by iopamidol optic neurography.
Cavernous degeneration of the optic nerve has been described predominantly in association with long-standing glaucoma, although less frequently it has been reported in other, disparate disease processes. The only descriptions to date have been in pathologic specimens in vitro. This is the first report to describe syrinx formation of the optic nerves in vivo in two patients with nonglaucomatous ...
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ژورنال
عنوان ژورنال: Radiology Case Reports
سال: 2021
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2021.01.017